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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f1c7ecd47c482509b29e750aae2a32d8ba9c55426d7cefadce16e0261936438' 
  AND token = 'S5kBRdYy1HmjY+FgSUbdwNfJBO0q6bFu3y4rGfHINqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}