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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b25144d42b4355a08538bc1786c7a3a93a568dc56c366971d2fa9c443036eaf7' 
  AND token = 'fictaNq6SsS1Sf5PGamn/mkI9TgVkxZV+4HcCPT/UV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}