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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f47a142bff1a5ee5ead385d71c08d566be973a3fcd2bc7624ca1160e06cdd18c' 
  AND token = 'UNc2niV0MCQZT+PofXzwxOcpFn2U1qgRxa1rlmiOFZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}