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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e38f86a99863d88f355dd6576472d4172788c08f2a9e200cb27e8555d1cab5e9' 
  AND token = 'do+p3dG0eZmK8gsr71zNx/1WDJqk47BRtU+9gsi6RDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}