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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c46f9140e2a5b6bb1eb88c793f5284b0337231d0081efabc82022847635ee14f' 
  AND token = '7X3T0tZWVoA8sRx0IKc/GvFxUfr+TweBhI8p6Om8Ho8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}