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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d318ce64fd190e74350c915db4274e9421d757e191f48e223af7b7c2704901c' 
  AND token = '+iawHLs+wumiVP9i9C9Mar/FvpBebNurlwkFhOb2TXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}