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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a65259aa15b35c0856d1a2093a0184161853a2cf99e0f2803484a7d805ee111' 
  AND token = 'iFDzo/zRXTIQr7mhoITTAkUWEImb9gdwScyLdExW5F4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}