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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c42ac48815a69b5e92702c30106225983ad45153b78e77ae4e4b728df49a1e7' 
  AND token = 'f4G8/zC3E9DpfrRhSjf2oHhb5EMjZY6G7+IXA8NBAJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}