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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '140ab12cbc699ebd502f6a4fcd2c7159fae53e73b37d21bd879c189534f88067' 
  AND token = 'w8uSg1H4uOjVqai26y1iK/tO6P5WZ5uo0UKBHwtZdUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}