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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '359ae6ea45c620e53c50dee15ab2b6753b4ba645f202a45d495ee8cb5d204e60' 
  AND token = 'ckWO3ZvTTEbNdEFd3bbPWUtBTgs6zwFm1yV+gmg5xEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}