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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '904c722aff96f82d02a490d5ca3544bd222c538b5c3b41884d6c311f86ecf243' 
  AND token = 'n7/msyuuLjzXy6X1nh5oVLw0WQmFu6Zy6MBFdpDS0g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}