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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edfd55c1eef9342de423ef8b1c4a9ed99d8bd030e15f7cfa28500c5c1b579754' 
  AND token = 't1RQQbQ4MMXiFF2tchv+jrHYVl6w2l3aAPMQ+eRYLY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}