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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9558c544af061039217fd86423213402255e28f3cc07dcea84fdc7663df10f74' 
  AND token = 'IVKajq/0h8UPsgRR8b6My81dcoFvU6W2wd0aAbZ6aRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}