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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b5dad7330b7a627542daf3f2e9aef1120eab5ad01059200db31423def1b6c51' 
  AND token = 'ucheJqBwg1UDGT9KelRIKOqsFqF5dmjGlxJglHkdXmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}