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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4c4e3d9659fc9806f2a58344eaa7bb3c9ec7851af783ebee5a1229603832e09' 
  AND token = '5sO3I7DRIwPgB2NB6C3l6wkiVXWzZDuxyObxdBGzChk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}