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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d0ccfd466e91bb4fd938b287fdbe20ef99a1991aab7d2c9c81c7fd84929908d' 
  AND token = '217ja4Lh3pIeg2tOyxWu1j9oYVhcrMfhL0Nv0LZuniw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}