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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f66a6e4e4364afd49bbb1312b22b38dc16466fc2d1689a90f0f024dff9704ee' 
  AND token = '58DIsape+7LmSwpgANY2CsN5kYylv4xNd9uWipfIKBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}