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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a01116f2610746782c0cdbade36f33843d6271bc3d04758d0de5b06aba3fc390' 
  AND token = 'FXRYVd6UpWH1To1oVIIGNNvboOQ7NCYfU2bP0Ew52Lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}