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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '824c5b81f9830f6c15c1fcf8e30a015a8c48195f4f4106ba307d9c7fba60d0fe' 
  AND token = 'ejY3XipaBkPe9wVW09ZZuE82BSDiKSRo7yyQ0MU6bkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}