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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54523854b1522def75a646e221e8dcd8a5f4a06a9ea05a2a9c9b9e07bb756d40' 
  AND token = 'Bc9TsgqzcbOg5GlhrpYi/45Sb3noaEHxLI56jvFSHqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}