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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0500d78729a69168d3fb53abd6eb72eb3987397ae10bb2859a9493a59205463' 
  AND token = '4I87/Ml0H0ykFNQnK5xR6t4KbUGQ0l6yNtiQol7deUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}