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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e2bd4768dbe1e6e01a5ea860e7bbc29306e5245e68a492ccc27f7f2ff1a6583' 
  AND token = 'dEc9C8vj54aMuYjl5Zr0FYz7qNv96Da2R46MtSbcyo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}