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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbc85dc5b70178c3a4f28bd4384be3e0e6e7c3864d122c29df126fd5c5ea9485' 
  AND token = 'Zcefd8IhXnKelc6pgEQZTEyDAD2iQl243uFe1QdiUpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}