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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5581969b6de540171a3bae0a894cffa134656bc1213c539c6477ad1e1636003' 
  AND token = 'S3Duto2CTW7yWDG2qesjmokn5i8ngLcwu1lNJrgZ+GU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}