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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49999871c3d20c17e31c6f934bf2ac071e6b9e954665670f7d12910ce6ac2c9' 
  AND token = '1GTZCsDOp6SaJQx0TzbjxfpOH/N9DqdBjLvTyJ6Uwl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}