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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ae18f2de8df0e47fed333a37bbb8c4036972515b578a7cd0e56078fd24de922' 
  AND token = '2A8NWtjtI6OTGpoi706dV9JNoLZd5ckvCtePHGJrOvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}