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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3229a42082f413b2075fbd10995dd2d884926c1cdabece8f27d952db147ec100' 
  AND token = 'pZUx4xCPgeYbtBRnhjCpIhiARBkU/IbV0/G6ZGsSMWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}