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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70bc389f7efe53bb1b42870356be001a4353b07d80726e9bdb82e561c4c0ff13' 
  AND token = 'I87mtph9+I8q5LxuMwuqiVtWd36RaG5bGtzTqMCnRZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}