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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24a65241b6dcb5f452452a02268eb63f0c6f71dacd7b7d002ee8a93a52baf435' 
  AND token = 'EI8EfkMNtqILG94xuP2fbG6Xhyvb+8BbVG/vBrdiu+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}