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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4dfa08ed7a8a857a6576a92d500a0c616e685366edf74eb291e383888d4f1a1' 
  AND token = 'bEZCez7dDC3NkoHW3Qwp6xxnOhE85e8rkHczPj2UzQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}