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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d1380814119b875cbc8048a8bcbd61bb2ac35d79db74a2dada7cf7eaafd4c32' 
  AND token = 'rvvT7yk/rWZ11EqMOkEdVav3ysuJEMmyF/7X2Si4fQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}