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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caec65f7d95b4d5e3197ce2194c377a97b0638f369f05545c63194f3ee3c50bb' 
  AND token = 'aQr+Y5ORRA4xaPEpwElyUg9P1sW2wy0DajbzB6fqIQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}