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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a78e15fb66855bd0639f6ca9120af9f78cf2e0c7bf80717dfec35b54d5369a5f' 
  AND token = 'CqEMY4I31O6a0LUWcJOTYG6cuB+oWo+9mN96AsLAG6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}