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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25fa3a03aa24add19d6bef7b4adf6de7d57056e8579f60ca46feffa74f4dd4ac' 
  AND token = 'HbBjOSMn9bY4+a842yEuClCzK+MpOOlH4vg9+BRze6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}