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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4f2ff534ecd858ba315293d740c080c2680c05a4a1def0afefe741db85c4814' 
  AND token = '8ttgBkKTqUJngZhjEFUxw6jt0qEsHlqKANCC3KZs9RM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}