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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb531e1fd0763df0f3999de1fc0580a8eafdb2df2bcc817cd053dda28da2e95' 
  AND token = 'iINkKHOe0t2OhwfHA21Mw24wMtOZ+DyQCDKwN6wz6EE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}