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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01f3fc5a08d29ea102e5edd956e3a35a7bcbdfc0d5f6a18f3f909e70ffff8069' 
  AND token = 'fySTel8V6tNF8YoHAnEMNlO3XKBa69EP0S2pb2ImWiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}