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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78c5295d4610f5ca2e01dfc8162b1ee7c21e12933a3caa317ee99e5dacae217b' 
  AND token = '86O/Pxfnd049ZsvB175lF/84d2Z4N5Psk53rHergq7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}