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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c00498c819ccef28e521e85e81c4a0a81f1312b7e000da4e618e1544328a9d0' 
  AND token = 'tOfVL4VnCO9SHaUAuOF7Vwe+gqbsIkSuP8cszWlh6s0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}