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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8991209559ae94cfebb8005308fd0a41c3ae231c42a391d11470f48001cf6aec' 
  AND token = '+XkPHtUhGnkoBDoFUYhhOLXlIvCrhNMnDyj23QvEpeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}