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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d9328877ed7cc634058ea9d19bd66debc314742a13e83c7cd6d61e771fe5f05' 
  AND token = '+xIfUTOMc/m3n9nMiwo8SyuUf9P/osBeluQrPtVb6GU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}