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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4008c81ff6777e98f75533a88fa7ec2de519ae986ee761034d353e0fa8b3202' 
  AND token = 'esH+QhyNrDN38PNXRuxNGIVrf0PcW2KMuOzAatg5BmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}