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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e0840fc446fa157aff0228423a4c7b29a629557c44903c13d5a1d94a8a5973f' 
  AND token = 'zGo5VdxHL7NinrSkD6SjEKZG0lYgt/5t5uCXrG7msAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}