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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f638d4a3c007d12bbe525d6e897a0de142c3bf74870447d8b5a6639bb6fd859' 
  AND token = 'nV/CZfGYF8pMnZHvRZzEGL5d6yPK6V4oGG4NWmW8nDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}