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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad7bcd57d7507318feef65626b52cf47cfc6e2dd47512f57410765445f27e460' 
  AND token = 'lYypElixT9+MpkpNucO8RyDm4mqP3o87atzt73mR9is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}