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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fb8322317c3bc8fc5f28a30daa28b58ef7e51f06285428c5b975cca1c0f3f17' 
  AND token = '8Wbe/k0byZBQsaW5FG//SBXOaNIFk2/+OYxf4lsuop8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}