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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b25faf43893924e6aeb0b278cc69983df6e51ea8a9f457af1ae91c9b1f96c71f' 
  AND token = 'qn3IPHfpgYgsSfVuf4oOC6L/JLbn+To4vaZcQXmDmpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}