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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '406a9fe94a61c274926009ff3b01e0bc199853631c52c62446d9e7ea36690f69' 
  AND token = 'UxLcrFGbgOlj1sMqLgz9XVWU3413ABGYZTiqkdgTOJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}