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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f40aa077f14217149f91a1a367a48a409e9fa7f5d6befbccab767eecc6dc9ecd' 
  AND token = 'Pj8HOreOdjKb/9EmzIOx8fD+fInjdAVQnFHFe8DOJ5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}