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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca58eeb0fae550023d290046b8cfa8110ee8fbc6401f0228db34c21e995efcf9' 
  AND token = 'aoeKLO9dXjfDLJF0LYXrzAeCQQ2cIKCzSHNn4+psGPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}